SCHEMBL25877996

SCHEMBL25877996

CC(C)(C)c1nc(-c2ccccc2)nc(-c2ccc3c(ccc4ccccc43)c2)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
RECQL P46063 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 5/20 0.40
HPGD P15428 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HSD17B10 Q99714 3/20 0.39
CYP1B1 Q16678 3/20 0.39
HIF1A Q16665 1/20 0.39
PDPK1 O15530 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP1A2 P05177 3/20 0.38
TP53 P04637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ABCG2 Q9UNQ0 2/20 0.38
HPRT1 P00492 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25877989 0.95 ALDH1A1 (0.42) MAPTALDH1A1HPGDHSD17B10CYP1B1
SCHEMBL25877993 0.93 L3MBTL1 (0.41) MAPTSMN1; SMN2LMNAALDH1A1HPGD
SCHEMBL23473684 0.88 MEN1 (0.49) MAPTSMN1; SMN2LMNAALDH1A1HPGD
SCHEMBL22186526 0.87 MAPT (0.51) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL17691923 0.87 MAPT (0.51) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL22249759 0.86 MEN1 (0.44) MAPTSMN1; SMN2LMNAALDH1A1HPGD
SCHEMBL24306925 0.86 MAPT (0.50) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL23759341 0.86 HPRT1 (0.52) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL23759490 0.86 HPRT1 (0.52) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL24307048 0.86 MAPT (0.50) MAPTSMN1; SMN2NPC1LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM MAPT 1215/4885SMN1; SMN2 1669/4885NPC1 1759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.