SCHEMBL25878224

SCHEMBL25878224

CC(C)(C)c1cc2ncn(-c3ccccc3)c2cn1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 12/20 0.59
SRC P12931 2/20 0.53
HTT P42858 2/20 0.51
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
MAPK1 P28482 1/20 0.48
MAPK10 P53779 1/20 0.48
NCOA1 Q15788 1/20 0.48
NCOA3 Q9Y6Q9 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13618142 0.77 FGFR1 (0.65) FGFR1SRCHTTALDH1A1
SCHEMBL23846263 0.76 FGFR1 (0.76) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL7986978 0.74 FGFR1 (1.00) FGFR1SRCHTT
SCHEMBL10183206 0.74 GRM5 (0.38) HTTALDH1A1HPGD
Hydrochloric Acid SCHEMBL7975764 0.73 FGFR1 (0.97) FGFR1SRCHTT
SCHEMBL31294913 0.72 FGFR1 (0.68) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL19848102 0.72 FGFR1 (0.68) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL19467894 0.72 GABRA1 (0.63) FGFR1SRCHTT
SCHEMBL13993884 0.71 FGFR1 (0.76) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL23772972 0.71 KDR (0.57) FGFR1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM FGFR1 4273/4885SRC 2384/4885HTT 3418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.