SCHEMBL25878329

SCHEMBL25878329

c1ccc(-c2nc(-c3ccc4c(c3)-c3cccc(-c5cccc6c5oc5ccccc56)c3C43C4CC5CC(C4)CC3C5)nc(-c3ccc4ccccc4c3)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
PRKDC P78527 4/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
GGPS1 O95749 1/20 0.32
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 2/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.30
AVPR1A P37288 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25817530 0.88 ALOX5 (0.33) ALOX5PRKDCGGPS1KDM4EMEN1
SCHEMBL23605769 0.87 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25878324 0.87 ALOX5 (0.35) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25878331 0.86 ALOX5 (0.35) ALOX5PRKDCPIK3CDPIK3CBKDM4E
SCHEMBL23605788 0.84 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25035937 0.84 ALOX5 (0.35) ALOX5PRKDCPIK3CDPIK3CBKDM4E
SCHEMBL25038704 0.84 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25038137 0.84 MEN1 (0.33) KDM4EMEN1ALDH1A1KMT2ATP53
SCHEMBL25038259 0.84 ALOX5 (0.32) ALOX5
SCHEMBL25878333 0.84 PRKDC (0.38) ALOX5PRKDCPIK3CDPIK3CBGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ALOX5 1072/4885PRKDC 1991/4885PIK3CD 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.