SCHEMBL25878324

SCHEMBL25878324

c1ccc(-c2nc(-c3cc4c(c(-c5cccc6c5oc5ccccc56)c3)C3(c5ccccc5-4)C4CC5CC(C4)CC3C5)nc(-c3ccc4oc5ccccc5c4c3)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
PRKDC P78527 5/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
TSHR P16473 3/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 3/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 2/20 0.31
KDM4E B2RXH2 1/20 0.31
AVPR1A P37288 1/20 0.31
MAPT P10636 2/20 0.30
GGPS1 O95749 1/20 0.30
ATM Q13315 1/20 0.30
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
PTPRF P10586 1/20 0.30
PTPN2 P17706 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23605780 0.90 HTT (0.32) ALDH1A1LMNAMAPTHTT
SCHEMBL23605769 0.88 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBTSHR
SCHEMBL23606036 0.88 PLA2G2A (0.33) HTT
SCHEMBL23605770 0.88 ALDH1A1 (0.33) TSHRALDH1A1HPGDKMT2ALMNA
SCHEMBL25817538 0.88 ALOX5 (0.30) ALOX5TSHRALDH1A1HPGDKMT2A
SCHEMBL23605788 0.87 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CBTSHR
SCHEMBL25878329 0.87 ALOX5 (0.35) ALOX5PRKDCPIK3CDPIK3CBTSHR
SCHEMBL23605936 0.86 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBTSHR
SCHEMBL23606119 0.86 PLA2G2A (0.34) ALDH1A1HPGDKMT2ALMNAMEN1
SCHEMBL23605940 0.86 HTT (0.33) TSHRALDH1A1HPGDKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ALOX5 1072/4885PRKDC 1991/4885PIK3CD 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.