SCHEMBL25878375

SCHEMBL25878375

COc1c(C)ccc2c1oc1c(C)c(C)ccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.45
MCL1 Q07820 1/20 0.43
MAOA P21397 1/20 0.41
HPGD P15428 2/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
ESR2 Q92731 3/20 0.39
ESR1 P03372 2/20 0.39
PON1 P27169 1/20 0.39
NQO1 P15559 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11976504 0.83 MCL1 (0.55) KDM4EALDH1A1MCL1CSNK2A2CSNK2B
SCHEMBL25878382 0.81 MAOA (0.40) KDM4EALDH1A1MCL1MAOAHPGD
SCHEMBL17637325 0.81 ALDH1A1 (0.60) KDM4EALDH1A1MCL1MAOAHPGD
SCHEMBL25878377 0.79 MCL1 (0.39) KDM4EALDH1A1MCL1HPGDHSD17B10
SCHEMBL25878384 0.79 MAOA (0.38) KDM4EALDH1A1MAOAHPGDTSHR
SCHEMBL25878383 0.78 MAOA (0.37) KDM4EALDH1A1MAOAHPGDHSD17B10
SCHEMBL10079563 0.75 KDM4E (0.51) KDM4EALDH1A1MAOAHPGDHSD17B10
SCHEMBL25878380 0.75 MAOA (0.41) KDM4EALDH1A1MAOAHPGDHSD17B10
SCHEMBL21663117 0.75 ALDH1A1 (0.46) KDM4EALDH1A1MCL1MAOAHPGD
SCHEMBL21451570 0.72 MCL1 (0.50) KDM4EALDH1A1MCL1ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed