SCHEMBL25878384

SCHEMBL25878384

COc1c(C)ccc2c1oc1c(OC(F)(F)F)c(C)ccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.38
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 4/20 0.37
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
HPGD P15428 3/20 0.33
POLB P06746 2/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 2/20 0.33
MAOB P27338 1/20 0.33
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25878534 0.93 MAOA (0.32) MAOAALDH1A1KDM4E
SCHEMBL25878377 0.87 MCL1 (0.39) ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL25878532 0.85 ESR1 (0.31) ESR1ESR2
SCHEMBL25878529 0.84
SCHEMBL25878383 0.82 MAOA (0.37) MAOAALDH1A1KDM4ECA12CA1
SCHEMBL25878382 0.79 MAOA (0.40) MAOAALDH1A1KDM4ECA12CA1
SCHEMBL25878375 0.79 KDM4E (0.45) MAOAALDH1A1KDM4ECA12CA1
SCHEMBL25878530 0.78 ALDH1A1 (0.37) ALDH1A1HPGDPOLBMAOBGAA
SCHEMBL25857976 0.73 SCN8A (0.30) MAPT
SCHEMBL12433435 0.73 SCN8A (0.36) KDM4EPOLBGAAEPHX2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed