SCHEMBL25878456

SCHEMBL25878456

c1ccc2c(c1)-c1cc(-c3cccc4c3oc3ccccc34)c(-c3ccc(-c4ccc(-c5cccc6ccccc56)cc4)cc3)cc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.37
PRKDC P78527 4/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
GGPS1 O95749 1/20 0.32
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
AVPR1A P37288 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23605787 0.82 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25878340 0.81 TSHR (0.33) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL22780164 0.81 ALOX5 (0.36) ALOX5PRKDC
SCHEMBL23614538 0.81 ALOX5 (0.36) ALOX5PRKDCGGPS1
SCHEMBL24622872 0.81 ALOX5 (0.42) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25878450 0.80 ALOX5 (0.33) ALOX5
SCHEMBL25879127 0.80 ALOX5 (0.44) ALOX5PRKDCGGPS1AVPR1A
SCHEMBL25878462 0.80 ALOX5 (0.44) ALOX5PRKDCGGPS1AVPR1A
SCHEMBL23614232 0.79 ALOX5 (0.36) ALOX5PRKDCGGPS1
SCHEMBL22788002 0.79 ALOX5 (0.36) ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ALOX5 1072/4885PRKDC 1991/4885PIK3CD 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.