SCHEMBL25878462

SCHEMBL25878462

c1ccc(-c2ccc(-c3ccc(-c4ccc5c(c4)C4(c6ccc(-c7cccc8c7oc7ccccc78)cc6-5)C5CC6CC(C5)CC4C6)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
GGPS1 O95749 1/20 0.39
PRKDC P78527 8/20 0.37
PTGES2 Q9H7Z7 1/20 0.35
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
AVPR1A P37288 1/20 0.31
PDK2 Q15119 1/20 0.31
ATM Q13315 1/20 0.31
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25879127 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL25501083 0.91 ALOX5 (0.37) ALOX5GGPS1PRKDCPTGES2
SCHEMBL25878461 0.90 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL25879031 0.89 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL23614129 0.89 ALOX5 (0.39) ALOX5GGPS1PRKDCPTGES2
SCHEMBL25878359 0.89 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL25878385 0.88 ALOX5 (0.35) ALOX5GGPS1PRKDCPDK2PLA2G2A
SCHEMBL25878471 0.87 ALOX5 (0.35) ALOX5GGPS1PLA2G2APLA2G4A
SCHEMBL25878945 0.87 ALOX5 (0.36) ALOX5GGPS1PRKDCPDK2PLA2G2A
SCHEMBL25878451 0.87 ALOX5 (0.39) ALOX5GGPS1PRKDCPTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ALOX5 1072/4885GGPS1 526/4885PRKDC 1991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.