Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585656 | 1.00 | FFAR2 (0.35) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2584839 | 0.90 | RIPK1 (0.30) | — | |
| SCHEMBL2581022 | 0.90 | RIPK1 (0.30) | — | |
| SCHEMBL4509815 | 0.88 | FFAR2 (0.34) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4509140 | 0.88 | FFAR2 (0.34) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4509143 | 0.88 | FFAR2 (0.34) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2584668 | 0.87 | SLC6A2 (0.36) | FFAR2ATM | |
| SCHEMBL2584669 | 0.87 | SLC6A2 (0.36) | FFAR2ATM | |
| SCHEMBL2578423 | 0.84 | FFAR2 (0.39) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4087759 | 0.82 | FFAR2 (0.37) | FFAR2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |