Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578264 | 0.90 | OPRK1 (0.36) | OPRK1ALDH1A1PKM | |
| SCHEMBL4509292 | 0.86 | FFAR2 (0.43) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2587846 | 0.84 | FFAR2 (0.35) | FFAR2OPRK1PSEN1PSEN2APH1B | |
| SCHEMBL2585656 | 0.84 | FFAR2 (0.35) | FFAR2OPRK1PSEN1PSEN2APH1B | |
| SCHEMBL2581482 | 0.82 | PSEN1 (0.36) | FFAR2OPRK1PSEN1PSEN2APH1B | |
| SCHEMBL2585664 | 0.79 | FFAR2 (0.35) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2587848 | 0.79 | FFAR2 (0.35) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2585660 | 0.79 | FFAR2 (0.35) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4509140 | 0.79 | FFAR2 (0.34) | FFAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4509143 | 0.79 | FFAR2 (0.34) | FFAR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |