SCHEMBL25878685

SCHEMBL25878685

c1cc(-c2ccc(-c3ccc4c(c3)sc3ccccc34)cc2)c2c(c1)-c1cc(-c3cccc4c3sc3ccccc34)ccc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
PRKDC P78527 1/20 0.36
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25878687 0.91 ALOX5 (0.48) ALOX5PRKDC
SCHEMBL25878686 0.85 ALOX5 (0.42) ALOX5PRKDC
SCHEMBL25878696 0.83 ALOX5 (0.42) ALOX5PRKDC
SCHEMBL25878625 0.83 PRKDC (0.33) PRKDC
SCHEMBL25817676 0.82 ALOX5 (0.42) ALOX5PRKDC
SCHEMBL25878640 0.81 F9 (0.33) ALOX5ALDH1A1MAPTHPGDRAB9A
SCHEMBL25614639 0.81 ALDH1A1 (0.30) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL25878952 0.80 ALOX5 (0.41) ALOX5PRKDCALDH1A1MAPTHPGD
SCHEMBL23614566 0.80 ALOX5 (0.40) ALOX5PRKDC
SCHEMBL25878644 0.80 PIM3 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ALOX5 1072/4885PRKDC 1991/4885ALDH1A1 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.