Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893737 | 1.00 | GABRA1 (0.44) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL2923843 | 1.00 | GABRA1 (0.44) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| Hydrochloric Acid SCHEMBL25309438 | 0.99 | GABRA1 (0.44) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL28516119 | 0.95 | GABRA1 (0.43) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL25310982 | 0.94 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL26856071 | 0.93 | GABRA1 (0.44) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| Remimazolam SCHEMBL23735014 | 0.91 | GABRA1 (0.42) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| Remimazolam SCHEMBL29579211 | 0.91 | GABRA1 (0.42) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| Remimazolam SCHEMBL29379415 | 0.91 | GABRA1 (0.42) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| Remimazolam SCHEMBL846435 | 0.91 | GABRA1 (0.42) | GABRA1GABRA5GABRA2GABRB2GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708368-B2 | Crystal form of ethyl (S)-3-(8-bromo-1-methyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,2-a][1,4]diazepin-4-yl)propanoate hydrochloride | JIANGSU NHWALUOKANG PHARMACEUTICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2023-07-25 | — | — | US | disclosed |
| US-11708368-B2 | Crystal form of ethyl (S)-3-(8-bromo-1-methyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,2-a][1,4]diazepin-4-yl)propanoate hydrochloride | JIANGSU NHWALUOKANG PHARMACEUTICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708368-B2 | Crystal form of ethyl (S)-3-(8-bromo-1-methyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,2-a][1,4]diazepin-4-yl)propanoate hydrochloride | GABRA1, GABRA3, GABRA6 | GABRA1 1/4885GABRA5 4/4885GABRA2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.