SCHEMBL25879031

SCHEMBL25879031

Clc1ccc2c(c1)-c1ccc(-c3cccc4c3oc3ccccc34)cc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
GGPS1 O95749 1/20 0.36
PRKDC P78527 5/20 0.36
AHR P35869 2/20 0.34
PTGES2 Q9H7Z7 1/20 0.32
PDK2 Q15119 2/20 0.31
AVPR1A P37288 1/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
TNKS O95271 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25878462 0.89 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2PDK2
SCHEMBL25879127 0.89 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2PDK2
SCHEMBL24622872 0.84 ALOX5 (0.42) ALOX5GGPS1PRKDCPTGES2AVPR1A
SCHEMBL25878461 0.83 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2AVPR1A
SCHEMBL25879074 0.83 ALOX5 (0.39) ALOX5GGPS1PRKDCAVPR1A
SCHEMBL25818602 0.82 AHR (0.43) ALOX5PRKDCAHRPDK2AVPR1A
SCHEMBL25452307 0.82 ALOX5 (0.39) ALOX5GGPS1PRKDC
SCHEMBL25879023 0.81 AHR (0.42) AHRPDK2TNKS
SCHEMBL25878990 0.81 AHR (0.48) AHRPDK2TNKSATM
SCHEMBL23605787 0.81 ALOX5 (0.39) ALOX5GGPS1PRKDCAVPR1AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ALOX5 1072/4885GGPS1 526/4885PRKDC 1991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.