Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 16/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512135 | 1.00 | BRAF (0.43) | BRAFMAP3K5SCN9A | |
| SCHEMBL25879884 | 0.92 | SCN9A (0.39) | BRAFMAP3K5SCN9A | |
| SCHEMBL25879561 | 0.85 | BRAF (0.45) | BRAFMAP3K5 | |
| SCHEMBL25879708 | 0.84 | BRAF (0.52) | BRAFMAP3K5 | |
| SCHEMBL25879550 | 0.82 | MAP3K5 (0.54) | BRAFMAP3K5 | |
| SCHEMBL30512112 | 0.82 | MAP3K5 (0.54) | BRAFMAP3K5 | |
| SCHEMBL30512129 | 0.82 | BRAF (0.59) | BRAFMAP3K5 | |
| SCHEMBL25879551 | 0.82 | BRAF (0.59) | BRAFMAP3K5 | |
| SCHEMBL25879555 | 0.81 | BRAF (0.55) | BRAF | |
| SCHEMBL25882124 | 0.80 | MAP3K5 (0.63) | BRAFMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138412-A1 | FUSED PYRIMIDIN-2-AMINE COMPOUNDS AS CDK20 INHIBITORS | INSILICO MEDICINE IP LIMITED (CN) | 2023-07-27 | — | — | WO | disclosed |