SCHEMBL25879716 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	PTK2	Q05397	10/20	0.39

▸	CDK2	P24941	5/20	0.36

▸	CCNE1	P24864	2/20	0.36

▸	NQO2	P16083	1/20	0.34

▸	CDK7	P50613	4/20	0.34

▸	CCNH	P51946	4/20	0.34

▸	MNAT1	P51948	4/20	0.34

▸	CCNA2	P20248	3/20	0.34

▸	CCNK	O75909	2/20	0.34

▸	CDK12	Q9NYV4	2/20	0.34

▸	CSNK1D	P48730	1/20	0.33

▸	CYP2C9	P11712	1/20	0.33

▸	NAMPT	P43490	1/20	0.33

▸	PKMYT1	Q99640	1/20	0.32

▸	PTK2B	Q14289	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30512116	0.82	CDK2 (0.41)	PTK2CDK2CCNE1CDK7CCNH
SCHEMBL25881896	0.82	CDK2 (0.41)	PTK2CDK2CCNE1CDK7CCNH
SCHEMBL25881879	0.82	CDK7 (0.42)	PTK2CDK2CCNE1CDK7CCNH
SCHEMBL30512101	0.82	CDK7 (0.42)	PTK2CDK2CCNE1CDK7CCNH
SCHEMBL25879887	0.77	MAP4K1 (0.42)	—
SCHEMBL25881870	0.73	ALDH1A1 (0.41)	CDK2
SCHEMBL25881895	0.72	CREBBP (0.46)	PTK2
SCHEMBL30512112	0.71	MAP3K5 (0.54)	CDK2
SCHEMBL25879550	0.71	MAP3K5 (0.54)	CDK2
SCHEMBL25882093	0.71	BRAF (0.37)	CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023138412-A1	FUSED PYRIMIDIN-2-AMINE COMPOUNDS AS CDK20 INHIBITORS	INSILICO MEDICINE IP LIMITED (CN)	2023-07-27	—	—	WO	disclosed