SCHEMBL25880361

SCHEMBL25880361

Cc1cccc(-c2ccc3c4c2c2ccccc2n4c2ccc(-c4cccc(C)c4)c4c5ccccc5n3c42)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KMT2A Q03164 2/20 0.42
ENPP1 P22413 1/20 0.39
MAPT P10636 2/20 0.39
HSD17B10 Q99714 1/20 0.39
RXFP1 Q9HBX9 2/20 0.37
TP53 P04637 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
CNR2 P34972 2/20 0.37
CNR1 P21554 1/20 0.37
CHEK1 O14757 1/20 0.37
MAP4K4 O95819 1/20 0.37
ABL1 P00519 1/20 0.37
NTRK1 P04629 1/20 0.37
LCK P06239 1/20 0.37
FYN P06241 1/20 0.37
CSF1R P07333 1/20 0.37
MET P08581 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25880364 0.92 ENPP1 (0.38) NPC1RAB9AKMT2AENPP1MAPT
SCHEMBL25880370 0.88 BRD9 (0.42) KMT2AMAPTHSD17B10CNR2CNR1
SCHEMBL25880382 0.85 HSD17B10 (0.36) NPC1RAB9AKMT2AMAPTHSD17B10
SCHEMBL25880354 0.82 HSD17B10 (0.41) NPC1RAB9AKMT2AMAPTHSD17B10
SCHEMBL25880402 0.80 HSD17B10 (0.37) MAPTHSD17B10ALDH1A1L3MBTL1NR3C1
SCHEMBL25880383 0.79 HSD17B10 (0.35) NPC1RAB9AKMT2AMAPTHSD17B10
SCHEMBL19011050 0.78 NPC1 (0.47) NPC1RAB9AKMT2AMAPTHSD17B10
SCHEMBL19011065 0.78 NPC1 (0.47) NPC1RAB9AKMT2AMAPTHSD17B10
SCHEMBL25880372 0.78 CYP1A2 (0.40) RAB9AKMT2AMAPTCHEK1NTRK1
SCHEMBL25471298 0.76 MAPT (0.36) RAB9AKMT2AMAPTNTRK1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, NQO1 NPC1 4660/4885RAB9A 2405/4885KMT2A 652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.