SCHEMBL25880382

SCHEMBL25880382

c1ccc(-c2cccc(-c3ccc4c5c3c3ccccc3n5c3ccc(-c5cccc(-c6ccccc6)c5)c5c6ccccc6n4c53)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.36
PRKDC P78527 2/20 0.33
CAMK2D Q13557 1/20 0.32
NR3C1 P04150 1/20 0.32
PTGER1 P34995 1/20 0.32
PTGER4 P35408 1/20 0.32
PTGER3 P43115 1/20 0.32
PTGER2 P43116 1/20 0.32
KMO O15229 1/20 0.32
MAOA P21397 1/20 0.32
TSPO P30536 1/20 0.32
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
HTT P42858 2/20 0.31
APAF1 O14727 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
XBP1 P17861 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25880383 0.93 HSD17B10 (0.35) HSD17B10PRKDCPTGER1PTGER4PTGER3
SCHEMBL25880402 0.92 HSD17B10 (0.37) HSD17B10NR3C1MAPTL3MBTL1KDM4E
SCHEMBL25880422 0.91 ALK (0.35) NR3C1PTGER1PTGER4PTGER3PTGER2
SCHEMBL25880354 0.89 HSD17B10 (0.41) HSD17B10PTGER1MEN1MAPTKMT2A
SCHEMBL21262984 0.88 HSD17B10 (0.35) HSD17B10PRKDCCAMK2DPTGER1PTGER4
SCHEMBL20857879 0.87 HSD17B10 (0.34) HSD17B10PRKDCCAMK2DPTGER1PTGER4
SCHEMBL25880361 0.85 NPC1 (0.42) HSD17B10NR3C1MAPTKMT2ANPC1
SCHEMBL25880425 0.84 NR3C1 (0.35) HSD17B10NR3C1MAOATSPOMEN1
SCHEMBL25459746 0.84 TSPO (0.38) HSD17B10TSPOMEN1MAPTKMT2A
SCHEMBL25459787 0.84 TSPO (0.38) HSD17B10TSPOMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, NQO1 HSD17B10 1229/4885PRKDC 3164/4885CAMK2D 4004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.