SCHEMBL25880434

SCHEMBL25880434

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c6c4c4ccccc4n6c4ccc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)c6c7ccccc7n5c64)ccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ATM Q13315 1/20 0.49
JAK2 O60674 1/20 0.34
JAK3 P52333 1/20 0.34
PTGER4 P35408 1/20 0.34
KMT2A Q03164 3/20 0.33
IL1R1 P14778 1/20 0.33
HDAC4 P56524 1/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KDR P35968 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 2/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
BRCA1 P38398 1/20 0.32
PTPN1 P18031 1/20 0.32
TSPO P30536 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17146800 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL20857789 0.91 L3MBTL1 (0.45) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL25880473 0.89 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL24078682 0.85 ATM (0.39) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL16850078 0.85 L3MBTL1 (0.50) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL16850057 0.85 L3MBTL1 (0.44) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL22178729 0.85 L3MBTL1 (0.53) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL20857851 0.84 L3MBTL1 (0.41) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL20444344 0.84 L3MBTL1 (0.46) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL17265062 0.84 KDM4E (0.38) L3MBTL1KDM4EATMPTGER4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, NQO1 L3MBTL1 1282/4885KDM4E 1533/4885ATM 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.