Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953054 | 0.86 | NPSR1 (0.49) | NPSR1ADORA2APOLBCYP2C9CYP2C19 | |
| SCHEMBL9296950 | 0.84 | NPSR1 (0.70) | NPSR1ADORA2ASMN1; SMN2 | |
| SCHEMBL9298604 | 0.82 | NPSR1 (0.49) | NPSR1ADORA2APOLBCYP2C9CYP2C19 | |
| SCHEMBL30489995 | 0.79 | SOS2 (0.38) | ADORA2APRMT5WDR77SOS2AHR | |
| SCHEMBL2956934 | 0.77 | KDM4A (0.47) | NPSR1ADORA2APOLB | |
| SCHEMBL3081407 | 0.76 | CTSK (0.36) | NPSR1ADORA2APRMT5WDR77SOS2 | |
| SCHEMBL16377546 | 0.76 | NPSR1 (0.51) | NPSR1ADORA2APOLBRECQLCYP2C9 | |
| SCHEMBL3081412 | 0.74 | ADH1B (0.39) | NPSR1ADORA2APRMT5WDR77SOS2 | |
| SCHEMBL9296706 | 0.74 | NPSR1 (0.50) | NPSR1SMN1; SMN2MTNR1A | |
| SCHEMBL2956236 | 0.74 | MAPK1 (0.40) | NPSR1ADORA2ASMN1; SMN2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |