SCHEMBL25880719

SCHEMBL25880719

N#Cc1ccc2c(c1)oc1c(-c3cc(F)ccn3)cccc12

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 7/20 0.37
TGFBR1 P36897 2/20 0.37
KDM4C Q9H3R0 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
TDO2 P48775 1/20 0.34
IDO1 P14902 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
ROCK2 O75116 1/20 0.33
ELANE P08246 1/20 0.33
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26408767 0.86 IDO1 (0.42) GRM5KDM4CIDO1CLK4ELANE
SCHEMBL22316499 0.85 GRM5 (0.43) GRM5ABCG2
SCHEMBL22316451 0.84 PRKDC (0.48) GRM5TGFBR1KDM4CABCG2TDO2
SCHEMBL26080533 0.81 IDO1 (0.36) GRM5TDO2IDO1ROCK2PIM1
SCHEMBL25880761 0.81 IDO1 (0.36) GRM5TDO2IDO1ROCK2PIM1
SCHEMBL25880741 0.81 GRM5 (0.35) GRM5TGFBR1ELANEPIM1CSNK2A2
SCHEMBL22316452 0.79 KDM4E (0.41) TDO2PIM1CSNK2A2CSNK2BPIM3
SCHEMBL26407251 0.79 GRM5 (0.50) GRM5ABCG2
SCHEMBL24425927 0.77 CCR1 (0.39) TDO2ELANEALOX5
SCHEMBL25880791 0.77 ELANE (0.35) GRM5IDO1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed