SCHEMBL22316451

SCHEMBL22316451

N#Cc1ccc2c(c1)oc1c(-c3cc(-c4ccccc4)ccn3)cccc12

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 7/20 0.48
GRM5 P41594 1/20 0.38
TGFBR1 P36897 1/20 0.38
TDO2 P48775 1/20 0.38
GABRG2 P18507 3/20 0.38
GABRB3 P28472 3/20 0.38
GABRA5 P31644 3/20 0.38
GABRA3 P34903 3/20 0.38
GABRA1 P14867 2/20 0.38
CLK4 Q9HAZ1 1/20 0.37
MYC P01106 1/20 0.37
PIM1 P11309 1/20 0.36
ALOX5 P09917 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
ABCG2 Q9UNQ0 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25066876 0.86 PIM1 (0.39) PRKDCGRM5TGFBR1TDO2GABRG2
SCHEMBL22316499 0.86 GRM5 (0.43) GRM5ABCG2
SCHEMBL25880719 0.84 GRM5 (0.37) GRM5TGFBR1TDO2CLK4PIM1
SCHEMBL26408767 0.84 IDO1 (0.42) PRKDCGRM5CLK4KDM4C
SCHEMBL22316447 0.81 PRKDC (0.51) PRKDCTGFBR1GABRG2GABRB3GABRA5
SCHEMBL25880741 0.81 GRM5 (0.35) PRKDCGRM5TGFBR1PIM1
SCHEMBL25066860 0.80 LPL (0.36) PRKDCTGFBR1MYC
SCHEMBL25636984 0.78 PRKDC (0.55) PRKDCGABRG2GABRB3GABRA5GABRA3
SCHEMBL22316452 0.77 KDM4E (0.41) TDO2PIM1ALOX5
SCHEMBL25880791 0.77 ELANE (0.35) PRKDCGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785839-B2 Organic light-emitting materials containing cyano-substituted ligand Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-10 US disclosed
US-20200251666-A1 ORGANIC LIGHT-EMITTING MATERIALS CONTAINING CYANO-SUBSTITUTED LIGAND Beijing Summer Sprout Technology Co., Ltd. (CN) 2020-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200251666-A1 ORGANIC LIGHT-EMITTING MATERIALS CONTAINING CYANO-SUBSTITUTED LIGAND L1CAM, CYBA, ICOSLG PRKDC 4619/4885GRM5 1109/4885TGFBR1 2658/4885
US-11785839-B2 Organic light-emitting materials containing cyano-substituted ligand L1CAM, CYBA, ICOSLG PRKDC 4619/4885GRM5 1109/4885TGFBR1 2658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.