SCHEMBL25880741

SCHEMBL25880741

N#Cc1ccc2c(c1)oc1c(-c3cc(-n4c5ccccc5c5ccccc54)ccn3)cccc12

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 14/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
PRKDC P78527 1/20 0.33
ELANE P08246 1/20 0.32
TGFBR1 P36897 1/20 0.32
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25880791 0.93 ELANE (0.35) GRM5KDM4EALDH1A1MAPTTSHR
SCHEMBL25880785 0.84 PRKDC (0.34) KDM4EPRKDCTGFBR1
SCHEMBL26408767 0.83 IDO1 (0.42) GRM5KDM4EALDH1A1MAPTTSHR
SCHEMBL22316499 0.82 GRM5 (0.43) GRM5KDM4EALDH1A1MAPTTSHR
SCHEMBL22316451 0.81 PRKDC (0.48) GRM5PRKDCTGFBR1PIM1
SCHEMBL25880719 0.81 GRM5 (0.37) GRM5ELANETGFBR1PIM1CSNK2A2
SCHEMBL26171181 0.80 MAPK14 (0.43) KDM4EALDH1A1MAPTPRKDC
SCHEMBL21758513 0.80 GRM5 (0.33) GRM5
SCHEMBL21397127 0.78 GRM5 (0.42) GRM5KDM4EALDH1A1MAPTTSHR
SCHEMBL21928335 0.77 PIM1 (0.31) GRM5PIM1CSNK2A2CSNK2BPIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed