SCHEMBL25880791

SCHEMBL25880791

N#Cc1ccc2c(c1)oc1c(-c3cc(-n4c5ccccc5c5cccnc54)ccn3)cccc12

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.35
GRM5 P41594 11/20 0.32
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4D Q08499 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
PRKDC P78527 1/20 0.31
IDO1 P14902 1/20 0.31
PTGER4 P35408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25880741 0.93 GRM5 (0.35) ELANEGRM5KDM4EALDH1A1MAPT
SCHEMBL26408767 0.79 IDO1 (0.42) ELANEGRM5KDM4EALDH1A1MAPT
SCHEMBL22316499 0.78 GRM5 (0.43) GRM5KDM4EALDH1A1MAPTTSHR
SCHEMBL25880785 0.78 PRKDC (0.34) KDM4EPRKDC
SCHEMBL22316451 0.77 PRKDC (0.48) GRM5PRKDC
SCHEMBL25880719 0.77 GRM5 (0.37) ELANEGRM5IDO1
SCHEMBL17463118 0.76 PDE4B (0.47) ELANEGRM5DDB1CRBNPDE4B
SCHEMBL23626699 0.75 ALOX5 (0.41) ALDH1A1TSHRPRKDC
SCHEMBL21914399 0.75 ALOX5 (0.42) KDM4EALDH1A1MAPTTSHRHTT
SCHEMBL21758513 0.75 GRM5 (0.33) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230240129-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-27 US disclosed