Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 17/20 | 0.61 |
| ▸ | LOX | P28300 | 14/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707275 | 0.82 | LOXL2 (0.52) | LOXL2LOXMAPK8FFAR1 | |
| SCHEMBL25880602 | 0.80 | LOX (0.57) | LOXL2LOXMMP13 | |
| Hydrochloric Acid SCHEMBL5709327 | 0.77 | FFAR1 (0.61) | HTTMAPK14SMN1; SMN2FFAR1 | |
| SCHEMBL18049121 | 0.77 | LOXL2 (0.80) | LOXL2LOXLMNACYP3A4HTT | |
| SCHEMBL25880968 | 0.77 | RECQL (0.42) | LOXL2LOX | |
| SCHEMBL25880555 | 0.77 | KLKB1 (0.46) | LOXL2LOX | |
| SCHEMBL25880800 | 0.77 | RECQL (0.42) | LOXL2LOXMAPK14 | |
| SCHEMBL27593863 | 0.76 | HPGD (0.61) | LMNACYP3A4HTTMMP13MAPK14 | |
| SCHEMBL2894154 | 0.76 | LOXL2 (0.71) | LOXL2LOXMAPK8MAPK10SMN1; SMN2 | |
| SCHEMBL18049194 | 0.76 | LOXL2 (1.00) | LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |