Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861896 | 0.80 | MAPT (0.60) | SMN1; SMN2MAPTGAATDP1PPID | |
| SCHEMBL25882263 | 0.79 | MAPT (0.44) | SMN1; SMN2MAPTGAATDP1PPID | |
| SCHEMBL20204574 | 0.79 | MAPT (0.52) | SMN1; SMN2MAPTGAATDP1PPID | |
| SCHEMBL19255773 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTGAATDP1PPID | |
| SCHEMBL10144042 | 0.77 | MEN1 (0.53) | SMN1; SMN2MAPTGAATDP1PPID | |
| SCHEMBL20204575 | 0.76 | MEN1 (0.51) | SMN1; SMN2MAPTGAATDP1PPID | |
| SCHEMBL21095906 | 0.75 | ADH1B (0.44) | SMN1; SMN2MAPTGAATDP1MEN1 | |
| SCHEMBL3562547 | 0.73 | CDC25B (0.48) | SMN1; SMN2MAPTGAATDP1PPID | |
| SCHEMBL3562552 | 0.73 | CDC25B (0.48) | SMN1; SMN2MAPTGAATDP1PPID | |
| SCHEMBL24709872 | 0.72 | MAPT (0.44) | SMN1; SMN2MAPTGAATDP1PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215532-A1 | PROGRAMMED CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2023-07-26 | — | — | EP | disclosed |