Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22680856 | 0.78 | ADH1B (0.43) | ADH1BADH1CADH1AADH7CYP2C9 | |
| SCHEMBL627479 | 0.77 | ADH1B (0.54) | ADH1BADH1CADH1AADH7CYP2C9 | |
| SCHEMBL25882191 | 0.75 | SMN1; SMN2 (0.44) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL24136384 | 0.75 | ADH1B (0.47) | ADH1BADH1CADH1AADH7CYP2C9 | |
| SCHEMBL26983698 | 0.75 | CYP2C9 (0.60) | ADH1BADH1CADH1AADH7CYP2C9 | |
| SCHEMBL22680702 | 0.74 | CA1 (0.40) | ADH1BADH1CADH1AADH7CYP2C9 | |
| SCHEMBL28522074 | 0.74 | ADH1B (0.50) | ADH1BADH1CADH1AADH7CYP2C9 | |
| SCHEMBL22680855 | 0.73 | ADH1B (0.39) | ADH1BADH1CADH1AADH7CYP2C9 | |
| SCHEMBL19181511 | 0.73 | ALDH1A1 (0.49) | ADH1BADH1CADH1AADH7CYP2C9 | |
| SCHEMBL21095759 | 0.72 | ADH1B (0.44) | ADH1BADH1CADH1AADH7CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083583-B1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS AND COMBINATIONS THEREOF | SAGIMET BIOSCIENCES INC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-2870150-B1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3 V BIOSCIENCES INC (US) | 2019-06-19 | — | — | EP | disclosed |