Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.62 |
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401430 | 0.84 | HTR1A (0.78) | HTR1AHTR2AHTR2CHTR2BHTR1D | |
| SCHEMBL25883538 | 0.83 | HTR1A (0.49) | HTR1AHTR2AHTR2CHTR2BHTR1D | |
| SCHEMBL25883534 | 0.83 | HTR1A (0.46) | HTR1AHTR2AHTR2CHTR2BHTR1D | |
| SCHEMBL25885648 | 0.82 | HTR2A (0.72) | HTR1AHTR2AHTR2CHTR2BHTR1D | |
| SCHEMBL25882505 | 0.82 | GPR84 (0.55) | HTR1AHTR2AHTR2CHTR2BHTR1D | |
| SCHEMBL25882719 | 0.81 | HTR1A (0.53) | HTR1AHTR2AHTR2CHTR2BHTR1D | |
| SCHEMBL25882602 | 0.81 | HTR1A (0.46) | HTR1AHTR2AHTR2CHTR2BHTR1D | |
| SCHEMBL25882823 | 0.80 | HTR1A (0.46) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL25882598 | 0.80 | MPO (0.60) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL25747524 | 0.77 | HTR1A (1.00) | HTR1AHTR2AHTR2CHTR2BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141595-A2 | FUNCTIONALIZED ALKYLAMINES | TERRAN BIOSCIENCES, INC. (US) | 2023-07-27 | — | — | WO | disclosed |