Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302659 | 0.88 | HDAC1 (0.53) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL9918342 | 0.84 | HTT (0.55) | LMNAKMT2AMAPTHTTALDH1A1 | |
| SCHEMBL5638460 | 0.80 | KMT2A (0.62) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL5507140 | 0.76 | HDAC1 (0.57) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL8853550 | 0.76 | HDAC1 (0.57) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL8853694 | 0.76 | MAOA (0.57) | HDAC1HDAC8HDAC6TP53LMNA | |
| SCHEMBL24654710 | 0.74 | ALDH1A1 (0.49) | LMNAKMT2AKIF11HTTALDH1A1 | |
| SCHEMBL29754329 | 0.74 | CA9 (0.57) | LMNAKMT2AKIF11ALDH1A1CRBN | |
| SCHEMBL2611058 | 0.74 | CA9 (0.57) | LMNAKMT2AKIF11ALDH1A1CRBN | |
| SCHEMBL3328663 | 0.74 | HDAC1 (0.55) | HDAC1HDAC8HDAC6TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141323-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-07-27 | — | — | WO | disclosed |