Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890258 | 0.80 | RAB9A (0.56) | KDM2BRAB9AMEN1HPGDKMT2A | |
| SCHEMBL25890252 | 0.80 | RAB9A (0.56) | KDM2BRAB9AMEN1HPGDKMT2A | |
| SCHEMBL25890294 | 0.80 | RAB9A (0.43) | CCR5RAB9ALMNAPOLBNPC1 | |
| SCHEMBL25890263 | 0.80 | POLB (0.42) | CCR5RAB9AMEN1HPGDKMT2A | |
| SCHEMBL15274088 | 0.74 | SSTR4 (0.38) | CCR5MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL25890295 | 0.74 | SLC6A3 (0.40) | CCR5RAB9ALMNANPC1CASP3 | |
| SCHEMBL15851078 | 0.72 | RAB9A (0.40) | CCR5PPARGPPARDPPARARAB9A | |
| SCHEMBL17217538 | 0.72 | RAB9A (0.40) | CCR5PPARGPPARDPPARARAB9A | |
| SCHEMBL25890299 | 0.71 | F11 (0.37) | CCR5RAB9ALMNANPC1CASP3 | |
| SCHEMBL391910 | 0.71 | CYP1A2 (0.56) | CCR5MEN1HPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |