Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947489 | 0.87 | MEN1 (0.39) | RAB9AMAPTALDH1A1ITGA4ACHE | |
| SCHEMBL6947493 | 0.87 | MEN1 (0.39) | RAB9AMAPTALDH1A1ITGA4ACHE | |
| SCHEMBL29476747 | 0.78 | ACHE (0.51) | RAB9AMAPTALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL1000380 | 0.78 | ACHE (0.51) | RAB9AMAPTALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL25890369 | 0.74 | ACHE (0.50) | ACHELMNATSHR | |
| SCHEMBL3136218 | 0.73 | P2RX7 (0.46) | ALDH1A1MEN1KMT2AMAPK1MTNR1A | |
| SCHEMBL468628 | 0.73 | KMT2A (0.40) | MEN1KMT2AMAPK1MTNR1AMTNR1B | |
| SCHEMBL17540272 | 0.70 | KMT2A (0.44) | RAB9AMAPTALDH1A1ITGA4ACHE | |
| SCHEMBL10761470 | 0.69 | ANPEP (0.46) | MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL15519819 | 0.68 | KMT2A (0.56) | RAB9AMAPTALDH1A1ITGA4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |