Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354098 | 0.78 | ACHE (0.53) | ACHETSHRNOS3NOS2NOTUM | |
| SCHEMBL29410363 | 0.78 | ACHE (0.53) | ACHETSHRNOS3NOS2NOTUM | |
| SCHEMBL354099 | 0.78 | ACHE (0.53) | ACHETSHRNOS3NOS2NOTUM | |
| SCHEMBL5970427 | 0.78 | ACHE (0.53) | ACHETSHRNOS3NOS2NOTUM | |
| SCHEMBL10298158 | 0.75 | ACHE (0.50) | ACHETSHRNOS3NOS2NOTUM | |
| SCHEMBL25890363 | 0.74 | RAB9A (0.36) | ACHETSHRLMNA | |
| SCHEMBL10298200 | 0.71 | ACHE (0.46) | ACHETSHRNOS3NOS2NOTUM | |
| SCHEMBL27866565 | 0.70 | MAOB (0.34) | ACHELMNA | |
| SCHEMBL28050335 | 0.70 | MAOB (0.34) | ACHELMNA | |
| SCHEMBL15340734 | 0.69 | LMNA (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |