Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 7/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345080 | 0.99 | MEN1 (0.52) | KMT2AMEN1TDP1FAAHTRPV1 | |
| SCHEMBL8346749 | 0.96 | GHSR (0.47) | KMT2AMEN1TDP1FAAHTRPV1 | |
| SCHEMBL8348221 | 0.86 | FAAH (0.46) | KMT2ATDP1FAAHTRPV1GHSR | |
| SCHEMBL8345284 | 0.84 | L3MBTL1 (0.55) | KMT2AFAAHTRPV1 | |
| SCHEMBL8345466 | 0.84 | FAAH (0.47) | KMT2AMEN1FAAHTRPV1GHSR | |
| SCHEMBL8345090 | 0.83 | FAAH (0.49) | KMT2AMEN1TDP1FAAHTRPV1 | |
| SCHEMBL8347812 | 0.83 | FAAH (0.47) | KMT2AMEN1FAAHTRPV1GHSR | |
| SCHEMBL25384603 | 0.81 | FAAH (0.62) | FAAHTRPV1GHSR | |
| SCHEMBL25890385 | 0.81 | CYP11B1 (0.39) | GHSRRAB9A | |
| SCHEMBL8347084 | 0.79 | FAAH (0.57) | FAAHTRPV1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |