Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366778 | 0.75 | SLC6A4 (0.41) | LMNAMEN1KMT2ANR3C1ALDH1A1 | |
| SCHEMBL23794996 | 0.75 | SLC6A4 (0.41) | LMNAMEN1KMT2ANR3C1ALDH1A1 | |
| SCHEMBL16335384 | 0.75 | SLC6A4 (0.41) | LMNAMEN1KMT2ANR3C1ALDH1A1 | |
| SCHEMBL27860397 | 0.73 | SIGMAR1 (0.44) | NPC1RAB9ASMN1; SMN2SIGMAR1TAAR1 | |
| SCHEMBL25890500 | 0.72 | NPC1 (0.46) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL22731047 | 0.72 | NPC1 (0.43) | NPC1RAB9ASIGMAR1TAAR1SLC18A2 | |
| SCHEMBL28411649 | 0.72 | TRPA1 (0.44) | NPC1RAB9ACA1CA2MMP2 | |
| SCHEMBL28411652 | 0.72 | TRPA1 (0.44) | NPC1RAB9ACA1CA2MMP2 | |
| SCHEMBL24105665 | 0.71 | NR3C1 (0.32) | MEN1KMT2ANR3C1 | |
| SCHEMBL25890544 | 0.71 | NR3C1 (0.32) | MEN1KMT2ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |