Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100976 | 0.77 | TSHR (0.46) | SLC6A4ALDH1A1 | |
| SCHEMBL2702542 | 0.77 | IDO1 (0.46) | EPHX2HTR2CSLC6A4HTR2AALDH1A1 | |
| SCHEMBL23023176 | 0.76 | EPHX2 (0.50) | EPHX2ALDH1A1KMT2AHTTGAA | |
| SCHEMBL8907879 | 0.76 | EPHX2 (0.50) | EPHX2ALDH1A1KMT2AHTTGAA | |
| SCHEMBL4480785 | 0.75 | EPHX2 (0.49) | EPHX2ALDH1A1MEN1KMT2ASGMS2 | |
| SCHEMBL9390747 | 0.73 | SIGMAR1 (0.50) | EPHX2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9505541 | 0.73 | EPHX2 (0.58) | EPHX2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL3411535 | 0.73 | KMT2A (0.47) | EPHX2ALDH1A1MEN1KMT2ASGMS2 | |
| SCHEMBL8874259 | 0.72 | CYP3A4 (0.57) | EPHX2ALDH1A1MEN1KMT2ASGMS2 | |
| SCHEMBL17896214 | 0.72 | HTT (0.51) | EPHX2HTR2CSLC6A4HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |