Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084228 | 0.74 | MAPT (0.44) | L3MBTL1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2832539 | 0.73 | HPGD (0.42) | L3MBTL1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25890717 | 0.72 | MEN1 (0.51) | L3MBTL1CYP1A2CYP3A4CYP2D6DRD3 | |
| SCHEMBL11379881 | 0.71 | MAPT (0.44) | POLBL3MBTL1MAPTCYP1A2CYP3A4 | |
| SCHEMBL2830906 | 0.69 | SLC6A3 (0.38) | L3MBTL1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27770438 | 0.69 | ALDH1A1 (0.37) | L3MBTL1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11388906 | 0.69 | MAPT (0.42) | POLBL3MBTL1MAPTCYP1A2CYP3A4 | |
| SCHEMBL25890721 | 0.69 | LMNA (0.43) | L3MBTL1NPSR1ALDH1A1HPGDRAB9A | |
| SCHEMBL12261588 | 0.68 | SLC6A3 (0.40) | L3MBTL1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9791528 | 0.68 | MAPT (0.44) | POLBL3MBTL1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |