Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25891495 | 0.99 | LMNA (0.37) | SMN1; SMN2LMNAGAAMAPK1HPGD | |
| SCHEMBL25891490 | 0.91 | LMNA (0.39) | LMNAMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL25891470 | 0.90 | ALDH1A1 (0.40) | SMN1; SMN2LMNAHPGDALDH1A1MAPT | |
| SCHEMBL30487150 | 0.85 | MEN1 (0.39) | SMN1; SMN2LMNAGAAMAPK1ALDH1A1 | |
| SCHEMBL21378330 | 0.85 | MEN1 (0.39) | SMN1; SMN2LMNAGAAMAPK1ALDH1A1 | |
| SCHEMBL30487158 | 0.84 | MEN1 (0.39) | SMN1; SMN2LMNAGAAMAPK1RAB9A | |
| SCHEMBL21378264 | 0.84 | MEN1 (0.39) | SMN1; SMN2LMNAGAAMAPK1RAB9A | |
| SCHEMBL21378319 | 0.84 | PTGS2 (0.44) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL30487152 | 0.84 | PTGS2 (0.44) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL25891491 | 0.79 | CA9 (0.34) | SMN1; SMN2GAARAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708338-B2 | Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof | NEUROPORE THERAPIES, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708338-B2 | Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof | TPMT, ABCB1, DPP8 | SMN1; SMN2 2745/4885LMNA 4022/4885GAA 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.