Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676961 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1A2CYP1B1HPGD | |
| SCHEMBL29991362 | 0.88 | GAA (0.60) | ALDH1A1CYP1A2HPGDMAPTTSHR | |
| SCHEMBL115661 | 0.88 | GAA (0.60) | ALDH1A1CYP1A2HPGDMAPTTSHR | |
| SCHEMBL28465659 | 0.88 | ALDH1A1 (0.49) | ALDH1A1CYP1A1CYP1A2CYP1B1HPGD | |
| SCHEMBL15457550 | 0.86 | EPHX1 (0.57) | ALDH1A1HPGDLPAR1MAPTGAA | |
| SCHEMBL11660515 | 0.85 | ALDH1A1 (0.73) | ALDH1A1CYP1A1CYP1A2CYP1B1HPGD | |
| SCHEMBL13282637 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1A2CYP1B1HPGD | |
| SCHEMBL24253966 | 0.85 | POLB (0.56) | ALDH1A1CYP1A1CYP1A2CYP1B1LPAR1 | |
| SCHEMBL2795277 | 0.85 | NPC1 (0.46) | ALDH1A1CYP1A1CYP1A2CYP1B1HPGD | |
| SCHEMBL31372038 | 0.85 | NPC1 (0.46) | ALDH1A1CYP1A1CYP1A2CYP1B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218187-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | UNIVERSITY OF DUNDEE (GB) | 2023-11-16 | — | — | WO | disclosed |
| EP-4276097-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | University Of Dundee (GB) | 2023-11-15 | — | — | EP | disclosed |
| US-9040019-B2 | Methods of detecting myelin basic protein | GENERAL ELECTRIC COMPANY (US) | 2015-05-26 | — | — | US | disclosed |
| CN-103025716-B | Bicyclic compound derivatives and their use as acc inhibitors | TAKEDA PHARMACEUTICAL | 2014-12-24 | — | — | CN | disclosed |
| US-20140154178-A1 | METHODS OF DETECTING MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2014-06-05 | — | — | US | disclosed |
| CN-103025716-A | Bicyclic compound derivatives and their use as acc inhibitors | TAKEDA PHARMACEUTICAL | 2013-04-03 | — | — | CN | disclosed |
| WO-2011136385-A1 | BICYCLIC COMPOUND DERIVATIVES AND THEIR USE AS ACC INHIBITORS. | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140154178-A1 | METHODS OF DETECTING MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | ALDH1A1 4638/4885CYP1A1 4866/4885CYP1A2 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.