SCHEMBL2589263

SCHEMBL2589263

CCCCCCCCCC[Si](C)(C)CCO[C@@]1(C(=O)O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.38
PYGB P11216 2/20 0.34
PTPN1 P18031 1/20 0.32
PRKCA P17252 7/20 0.31
PRKD3 O94806 1/20 0.31
PRKCG P05129 1/20 0.31
PRKCB P05771 1/20 0.31
PRKCH P24723 1/20 0.31
PRKCE Q02156 1/20 0.31
PRKCQ Q04759 1/20 0.31
PRKCD Q05655 1/20 0.31
PRKD1 Q15139 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2589260 1.00 MAPK1 (0.38) MAPK1PYGBPTPN1PRKCAPRKD3
SCHEMBL2122988 0.88 MAPK1 (0.44) MAPK1PYGBPTPN1PRKCAPRKD3
SCHEMBL1665805 0.88 MAPK1 (0.44) MAPK1PYGBPTPN1PRKCAPRKD3
SCHEMBL17781741 0.77 PYGB (0.43) MAPK1PYGB
SCHEMBL1279530 0.76 MAPK1 (0.40) MAPK1PYGBPRKCAPRKD3PRKCG
SCHEMBL1173142 0.72 PRKCA (0.39) MAPK1PYGBPRKCA
SCHEMBL1173608 0.72 PRKCA (0.39) MAPK1PYGBPRKCA
SCHEMBL28575710 0.72 PYGB (0.48) PYGB
SCHEMBL5062195 0.72 PYGB (0.48) PYGB
SCHEMBL9095367 0.71 PYGB (0.40) MAPK1PYGBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563337-B1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2017-07-26 EP disclosed
EP-2563337-A1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE Salama, Zoser B. (DE) 2013-03-06 EP disclosed
WO-2011134675-A1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2011-11-03 WO disclosed