⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211354 | 0.82 | TRPA1 (0.30) | — | |
| SCHEMBL1245585 | 0.80 | KDM4E (0.35) | — | |
| Quinoline SCHEMBL1162952 | 0.74 | TRPA1 (0.31) | — | |
| Cinnoline SCHEMBL450150 | 0.74 | TRPA1 (0.31) | — | |
| SCHEMBL1395835 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL206344 | 0.72 | TRPA1 (0.34) | — | |
| Quinoxaline SCHEMBL451431 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL6843536 | 0.71 | MAPT (0.39) | — | |
| SCHEMBL9432585 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL10434951 | 0.71 | MAPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9433 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145659-A1 | HETEROCYCLE FUSED GAMMA-CARBOLINES ACTING ON THE SEROTONINE 5-HT2A RECEPTOR | INTRA-CELLULAR THERAPIES, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| CN-118253348-A | Carbonylation catalyst, preparation method and application thereof | 万华化学集团股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| WO-2024112258-A1 | SEROTONIN RECEPTOR AS A TARGET FOR THERAPY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2024-05-30 | — | — | WO | claimed |
| EP-4361141-A1 | PROTEIN DEGRADATION AGENT | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2024-05-01 | — | — | EP | claimed |
| CN-117940431-A | Compound, light-emitting material, and light-emitting element | 九州有机光材股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| WO-2024074641-A1 | METHOD FOR PREPARING AMIDES FROM ESTERS | BASF SE (DE) | 2024-04-11 | — | — | WO | claimed |
| US-20240059726-A1 | GLYCOSYLATED HISTONE DEACETYLASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | GEORGIA TECH RESEARCH CORPORATION | 2024-02-22 | — | — | US | claimed |
| CN-117545749-A | Protein degradation agent | 苏州开拓药业股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| WO-2024027694-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2024-02-08 | — | — | WO | claimed |
| CN-117466884-A | Heterocyclic compounds or salts thereof as ATR kinase inhibitors, pharmaceutical compositions containing same and uses thereof | 德州大学系统董事会 | 2024-01-30 | — | — | CN | claimed |
| EP-0039051-B1 | MANNICH-BASE HYDROXAMIC ACID PRODRUGS FOR THE IMPROVED BIOAVAILABILITY OF NON-STEROIDAL ANTI-INFLAMMATORY AGENTS, A PROCESS FOR PREPARING AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | MERCK & CO. INC. (US) | 1985-07-24 | — | — | EP | claimed |
| EP-0148128-A2 | Optically active penem compounds | CIBA-GEIGY AG (CH) | 1985-07-10 | — | — | EP | claimed |
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | claimed |
| EP-0106800-A1 | Furans | CIBA-GEIGY AG (CH) | 1984-04-25 | — | — | EP | claimed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | claimed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | claimed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | claimed |
| EP-0039051-A2 | Mannich-base hydroxamic acid prodrugs for the improved bioavailability of non-steroidal anti-inflammatory agents, a process for preparing and a pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1981-11-04 | — | — | EP | claimed |
| US-3957726-A | S-TRIAZINE-IMIDE COPOLYMERS | CIBA-GEIGY CORPORATION (US) | 1976-05-18 | — | — | US | claimed |
| US-3946011-A | S-Triazine tetracarboxylic acids and dianhydrides | CIBA-GEIGY CORPORATION (US) | 1976-03-23 | — | — | US | claimed |