SCHEMBL1245585

SCHEMBL1245585

C1=Cc2ccccc2-c2ccccc2[N]1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ BCHE P06276 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ PTPRC P08575 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ IDO1 P14902 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ PTPN1 P18031 1/20 0.35
▸ ACHE P22303 1/20 0.35
▸ CES1 P23141 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ PTPN22 Q9Y2R2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25894 0.80 — —
SCHEMBL160697 0.78 ALDH1A1 (0.33) KDM4EMEN1ALDH1A1LMNABCHE
SCHEMBL160698 0.78 ALDH1A1 (0.33) KDM4EMEN1ALDH1A1LMNABCHE
SCHEMBL25254110 0.73 CDC25B (0.50) KDM4EMEN1ALDH1A1LMNABCHE
SCHEMBL8607730 0.73 — —
SCHEMBL223037 0.73 CDC25B (0.50) KDM4EMEN1ALDH1A1LMNABCHE
SCHEMBL224606 0.73 MEN1 (0.45) KDM4EMEN1ALDH1A1LMNABCHE
SCHEMBL9201732 0.73 KDM4E (0.35) KDM4EMEN1ALDH1A1LMNABCHE
SCHEMBL11150811 0.70 KDM4E (0.37) KDM4EMEN1ALDH1A1LMNABCHE
SCHEMBL2186647 0.70 KDM4E (0.33) KDM4EMEN1ALDH1A1LMNABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481174-B2 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device SAMSUNG DISPLAY CO., LTD. (KR) 2013-07-09 — — US claimed
US-7887932-B2 Organosiloxane compound and organic light-emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-02-15 — — US claimed
US-20070276160-A1 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device SAMSUNG DISPLAY CO., LTD. (KR) 2007-11-29 — — US claimed
US-20070155981-A1 Arylene derivative and organic light emitting device manufactured using the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-07-05 — — US claimed
US-20070048532-A1 Organosiloxane compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-03-01 — — US claimed
US-8481174-B2 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device SAMSUNG DISPLAY CO., LTD. (KR) 2013-07-09 — — US disclosed
US-7887932-B2 Organosiloxane compound and organic light-emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-02-15 — — US disclosed
US-20070276160-A1 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device SAMSUNG DISPLAY CO., LTD. (KR) 2007-11-29 — — US disclosed
US-20070155981-A1 Arylene derivative and organic light emitting device manufactured using the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-07-05 — — US disclosed
US-20070048532-A1 Organosiloxane compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-03-01 — — US disclosed
US-6063800-A Modulators of molecules with phosphotyrosine recognition units NOVO NORDISK A/S (DK) 2000-05-16 — — US disclosed
EP-0241427-A2 Compositions stabilised with di- or trisubstituted hydroxylamines and new di- or trisubstituted hydroylamines CIBA-GEIGY AG (CH) 1987-10-14 — — EP disclosed
US-4696964-A HEAT RESISTANCE, OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1987-09-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070048532-A1 Organosiloxane compound and organic light-emitting device comprising the same AOX1, PPOX, SQLE KDM4E 3310/4885MEN1 1448/4885ALDH1A1 195/4885
US-20070276160-A1 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device LEF1, EML4, LAS1L KDM4E 816/4885MEN1 1637/4885ALDH1A1 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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