Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671847 | 0.85 | MALT1 (0.58) | MALT1S1PR1HCAR3EPHX2IRAK4 | |
| SCHEMBL14520680 | 0.81 | MALT1 (0.52) | MALT1S1PR1BTKHCAR3EPHX2 | |
| SCHEMBL2402936 | 0.80 | MEN1 (0.58) | PDGFRBPDGFRABTKHCAR3 | |
| SCHEMBL2402934 | 0.80 | MEN1 (0.58) | PDGFRBPDGFRABTKHCAR3 | |
| SCHEMBL2400950 | 0.80 | ROCK2 (0.44) | PDGFRBPDGFRACD38S1PR1BTK | |
| SCHEMBL2400953 | 0.80 | ROCK2 (0.44) | PDGFRBPDGFRACD38S1PR1BTK | |
| SCHEMBL23304369 | 0.79 | MALT1 (0.52) | MALT1S1PR1HCAR3EPHX2MKNK1 | |
| SCHEMBL29779677 | 0.79 | S1PR1 (0.52) | MALT1S1PR1HCAR3EPHX2MKNK1 | |
| SCHEMBL29501518 | 0.78 | MALT1 (0.47) | MALT1S1PR1HCAR3EPHX2IRAK4 | |
| SCHEMBL7764412 | 0.77 | S1PR1 (0.55) | MALT1S1PR1HCAR3MKNK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |