Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | AOC1 | P19801 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764412 | 0.98 | S1PR1 (0.55) | S1PR1MALT1MEN1KMT2ACTSK | |
| SCHEMBL23304369 | 0.96 | MALT1 (0.52) | S1PR1MALT1MEN1KMT2ACTSK | |
| SCHEMBL1671847 | 0.92 | MALT1 (0.58) | S1PR1MALT1MEN1KMT2ACTSK | |
| SCHEMBL4006284 | 0.84 | HRH3 (0.58) | S1PR1MALT1MEN1KMT2AALDH1A1 | |
| SCHEMBL29501368 | 0.84 | HRH3 (0.58) | S1PR1MALT1MEN1KMT2AALDH1A1 | |
| SCHEMBL25426946 | 0.84 | MAPK1 (0.51) | S1PR1MALT1MEN1KMT2AALDH1A1 | |
| SCHEMBL14520680 | 0.84 | MALT1 (0.52) | S1PR1MALT1MEN1KMT2AALDH1A1 | |
| SCHEMBL2051027 | 0.82 | PRKCZ (0.50) | — | |
| SCHEMBL31127364 | 0.81 | MALT1 (0.47) | S1PR1MALT1EPHX2SCN9A | |
| SCHEMBL14980406 | 0.81 | MALT1 (0.50) | MALT1KDM4EALDH1A1L3MBTL1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751909-B | Preparation method of rebaudinib intermediate | 杭州福斯特药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-114751909-A | Preparation method of Ribociclib intermediate | 杭州福斯特药业有限公司 | 2022-07-15 | — | — | CN | disclosed |