Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23893409 | 0.86 | THRB (0.41) | — | |
| SCHEMBL23893631 | 0.81 | MAPT (0.41) | ALDH1A1GAAHPGDKDM4EMEN1 | |
| SCHEMBL23395514 | 0.81 | CYP3A4 (0.35) | PTPN1RXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL26854645 | 0.80 | KLK7 (0.42) | RXFP1ALDH1A1GAAHPGDMAOB | |
| SCHEMBL25896587 | 0.78 | CYP1A2 (0.33) | PTPN1APPCYP2C19 | |
| SCHEMBL23395487 | 0.77 | THRB (0.39) | PTPN1 | |
| SCHEMBL27107049 | 0.77 | THRB (0.39) | RXFP1ALDH1A1GAAHPGDMAOB | |
| SCHEMBL23395617 | 0.77 | THRB (0.42) | MAOBMEN1KMT2A | |
| SCHEMBL23395587 | 0.77 | PTPN1 (0.58) | PTPN1F2RL3APPALDH1A1GAA | |
| SCHEMBL22593635 | 0.77 | PTPN1 (0.39) | PTPN1AKR1C3AKR1C2APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-08-02 | — | — | EP | disclosed |