Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 17/20 | 0.45 |
| ▸ | FAP | Q12884 | 16/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26576887 | 0.93 | PREP (0.44) | PREPFAPDPP8DPP9ALB | |
| SCHEMBL26576636 | 0.93 | PREP (0.49) | PREPFAPDPP8DPP9ALB | |
| SCHEMBL25893738 | 0.88 | PREP (0.49) | PREPFAPDPP8DPP9FOLH1 | |
| SCHEMBL25895634 | 0.86 | PREP (0.56) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL26576870 | 0.86 | PREP (0.48) | PREPFAPDPP8DPP9FOLH1 | |
| SCHEMBL25893988 | 0.83 | PREP (0.49) | PREPFAPDPP8DPP9ALB | |
| SCHEMBL25893990 | 0.82 | PREP (0.54) | PREPFAPDPP8DPP9ALB | |
| SCHEMBL25893874 | 0.82 | PREP (0.54) | PREPFAPDPP8DPP9ALB | |
| SCHEMBL25896825 | 0.82 | FAP (0.43) | PREPFAPDPP8DPP9ALB | |
| SCHEMBL25893876 | 0.82 | PREP (0.50) | PREPFAPDPP8DPP9ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11707539-B2 | FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto | TRUSTEES OF TUFTS COLLEGE (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707539-B2 | FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto | FAP, APC, FIBP | PREP 543/4885FAP 1/4885DPP8 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.