Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 15/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898067 | 0.87 | GRM2 (0.47) | ALDH1A1GRM2GLO1 | |
| SCHEMBL25898581 | 0.83 | GRM2 (0.44) | KDM4EHTTGRM2GLO1 | |
| SCHEMBL25898569 | 0.79 | GRM2 (0.41) | KDM4EHTTGRM2GLO1 | |
| SCHEMBL25322091 | 0.77 | TIPARP (0.53) | — | |
| SCHEMBL25322085 | 0.77 | TIPARP (0.53) | — | |
| SCHEMBL30550893 | 0.77 | TIPARP (0.53) | — | |
| SCHEMBL25898732 | 0.76 | GRM2 (0.51) | GRM2 | |
| SCHEMBL25897776 | 0.75 | GRM2 (0.46) | KDM4EHTTGRM2GLO1 | |
| SCHEMBL26785843 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL25898159 | 0.73 | TIPARP (0.43) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |