Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 15/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898581 | 0.88 | GRM2 (0.44) | GRM2GLO1 | |
| SCHEMBL25898051 | 0.87 | KDM4E (0.44) | GRM2GLO1ALDH1A1 | |
| SCHEMBL25898569 | 0.83 | GRM2 (0.41) | GRM2GLO1 | |
| SCHEMBL26786770 | 0.81 | GRM2 (0.37) | GRM2TLR8GLO1ALDH1A1NPSR1 | |
| SCHEMBL25898732 | 0.80 | GRM2 (0.51) | GRM2 | |
| SCHEMBL25897776 | 0.79 | GRM2 (0.46) | GRM2TLR8GLO1 | |
| SCHEMBL25898373 | 0.79 | NPC1 (0.40) | GRM2TLR8ALDH1A1NPSR1 | |
| SCHEMBL25319383 | 0.75 | TIPARP (0.56) | — | |
| SCHEMBL25319387 | 0.75 | TIPARP (0.56) | — | |
| SCHEMBL25898801 | 0.74 | GRM2 (0.40) | GRM2TLR8GLO1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |