Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 5/20 | 0.38 |
| ▸ | TNF | P01375 | 5/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898407 | 0.88 | TIPARP (0.48) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25897799 | 0.88 | TIPARP (0.41) | TIPARPTNFTLR8GRM2HDAC3 | |
| SCHEMBL25898391 | 0.87 | TIPARP (0.46) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25899760 | 0.85 | TIPARP (0.41) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25898617 | 0.85 | TIPARP (0.41) | TIPARPTNFGRM2 | |
| SCHEMBL25898347 | 0.85 | BRD4 (0.40) | NPC1RAB9ATIPARPTNFTLR8 | |
| SCHEMBL26786720 | 0.84 | TIPARP (0.44) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25898843 | 0.83 | NPC1 (0.47) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25898123 | 0.83 | GRM2 (0.43) | TIPARPTNFGRM2HDAC3HDAC1 | |
| SCHEMBL26786770 | 0.81 | GRM2 (0.37) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |