Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22743267 | 0.85 | RAB9A (0.47) | AHRNPC1RAB9ATHRBRXFP1 | |
| SCHEMBL3970353 | 0.81 | THRB (0.41) | AHRTHRBRXFP1ALDH1A1HPGD | |
| SCHEMBL15507761 | 0.77 | HPGD (0.42) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL25895984 | 0.74 | MAPT (0.41) | THRBRXFP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL29439796 | 0.73 | HPGD (0.40) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL22715408 | 0.73 | HPGD (0.40) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5198021 | 0.73 | RAB9A (0.65) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4762536 | 0.73 | HTT (0.55) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL18809975 | 0.72 | ALDH1A1 (0.39) | THRBRXFP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL2221978 | 0.72 | AHR (0.55) | AHRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |