Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 16/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899203 | 0.87 | TLR8 (0.37) | KDM4EHTTGRM2TIPARP | |
| SCHEMBL26789113 | 0.85 | TIPARP (0.48) | HSD17B10KDM4EMEN1GAATSHR | |
| SCHEMBL25900007 | 0.85 | TIPARP (0.37) | KDM4EHTTGRM2TIPARP | |
| SCHEMBL25899110 | 0.85 | TIPARP (0.47) | HSD17B10KDM4EMEN1GAATSHR | |
| SCHEMBL25899963 | 0.84 | GRM2 (0.41) | GRM2TIPARP | |
| SCHEMBL25899251 | 0.84 | TIPARP (0.46) | KDM4ETSHRHTTGRM2TIPARP | |
| SCHEMBL25898801 | 0.82 | GRM2 (0.40) | KDM4EHTTGRM2ALDH1A1 | |
| SCHEMBL25898093 | 0.79 | LMNA (0.41) | KDM4ETSHRHTTGRM2TIPARP | |
| SCHEMBL25898794 | 0.79 | TIPARP (0.42) | KDM4EHTTGRM2TIPARP | |
| SCHEMBL25898816 | 0.79 | GRM2 (0.38) | GRM2TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |