SCHEMBL25899286

SCHEMBL25899286

O=C1c2ccc(Cc3ccc4c(c3)C(=O)N(c3ccccc3)C4=O)cc2C(=O)N1c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.62
NR1H3 Q13133 6/20 0.54
STAT3 P40763 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
PPARA Q07869 2/20 0.50
PPARD Q03181 1/20 0.50
ALDH1A1 P00352 1/20 0.49
GRM5 P41594 1/20 0.49
ESR2 Q92731 1/20 0.47
POLB P06746 1/20 0.47
NR1H2 P55055 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
SCN2A Q99250 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8605219 0.86 ESR1 (0.58) ESR1NR1H3PPARAPPARDALDH1A1
SCHEMBL4547161 0.85 MEN1 (0.64) ESR1NR1H3STAT3NPSR1PPARA
SCHEMBL25899292 0.83 BRD4 (0.57) ESR1NR1H3STAT3NPSR1PPARA
SCHEMBL25899305 0.82 ESR1 (0.74) ESR1NR1H3STAT3NPSR1ALDH1A1
SCHEMBL9480783 0.81 NR1H3 (0.66) NR1H3STAT3NPSR1PPARAPPARD
SCHEMBL9481335 0.80 NR1H3 (0.75) ESR1NR1H3ALDH1A1GRM5NR1H2
SCHEMBL18589041 0.79 ESR1 (0.68) ESR1NR1H3ALDH1A1ESR2CA12
SCHEMBL13433118 0.79 ALDH1A1 (0.56) ESR1STAT3NPSR1ALDH1A1ESR2
SCHEMBL10558482 0.78 ESR1 (0.57) ESR1NR1H3ALDH1A1GRM5ESR2
N-Phenyl-Phthalimide SCHEMBL123618 0.78 KMT2A (0.68) ESR1NR1H3NPSR1ALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230236508-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING PATTERNED CURED FILM, PATTERNED CURED FILM AND SEMICONDUCTOR ELEMENT RESONAC CORPORATION (JP) 2023-07-27 US disclosed